227 King St S (Sun Life Building)

[panamaniac]

I think the artist has taken some liberties, judging by the placement of what looks like the old TD Bank building (King at Frederick).  I could be wrong, but I think the church in the background would be the old St Peters Lutheran church.

Edit:  Actually, the building I took for the old TD bank could be an impression of the Federal Building on Duke St.  That would make more sense in terms of building placement.